Epic Quest Bio The case files
Case No. 110 · the exotic forty · have you seen this molecule?

KRYPTONITE

the plant enzyme that keeps SUPERMAN in disguise

File sealed

The detectives are still writing this one up. The poster and the facts are below; the film and the interrogation room open soon.

Booking photographs

KRYPTONITE, front view, against a height chart in nanometers
FRONT
KRYPTONITE, side view
SIDE · PDB 4QEO

The suspect, from its real atomic coordinates. Drag to turn it. Height chart in nanometers, a line every 2 nm. Shown on its DNA (dark), floppy loops left off. A thale cress plant is about twenty-five million times taller.

Rap sheet

Answers to
KRYPTONITE. KYP to friends, SUVH4 on paper.
Height
9.2 nm, standing on its DNA.
Weight
116 zeptograms, before it picks up any DNA.
Build
A reader for marked DNA, bolted to a writer for histones.
Habits
Flips a methylated C clean out of the DNA, then plugs the hole with two leucines.
Associates
CMT3. Each writes the mark the other reads. Round and round.
Victim
SUPERMAN, a flower gene. Its mutant flowers grow extra stamens.
Weakness
Methylated CG. It grips it weakly, and would not crystallize with one.
Last seen
In a crystal in an X-ray beam in New York, flipping a C out of DNA.
7

silenced copies of SUPERMAN in the first lineup: “the clark kent alleles.”
You’ve never seen one. That’s the disguise.

CASE FILE: Jackson, J. P. et al. (2002) Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 416, 556–560.

The poster on the street

The wanted poster for KRYPTONITE

This is the photocopied wanted poster for KRYPTONITE, No. 110 of the exotic forty. They were made for noticeboards around Boston, Cambridge and the rest of the east coast.

Found one? Scan its QR code with your phone. If you're a signed-in player, the sighting goes on your record with +1 XP.

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