Epic Quest Bio The case files
Case No. 117 · the exotic forty · have you seen this molecule?

Collagen IV sulfilimine

the first S=N bond found in biology, and why you need bromine

File sealed

The detectives are still writing this one up. The poster and the facts are below; the film and the interrogation room open soon.

Booking photographs

Collagen IV sulfilimine, front view, against a height chart in nanometers
FRONT
Collagen IV sulfilimine, side view
SIDE · PDB 1T60

The suspect, from its real atomic coordinates. Drag to turn it. Height chart in nanometers, a line every 2 nm. Welds shaded dark. The ropes it joins are each about forty times longer.

Rap sheet

Answers to
Sulfilimine, the nitrogen twin of a sulfoxide.
Height
9.4 nm, the welded joint.
Weight
250 zeptograms
Build
Six S=N welds join two 400 nm collagen ropes, head to head.
Accomplice
Peroxidasin, armed with hypobromous acid, the hot-tub sanitizer.
Associates
Bromine, preferred to chloride 50,000 to 1. Flies stripped of it almost never grow up.
Record
Ruled out by this mugshot’s own paper. Caught as S=N five years on.
Last seen
In a cow’s lens capsule, and in every basement membrane you own.
200,000,000,000,000,000

bromide ions in a teaspoon of your blood plasma, on average.
You’ve never seen one.

CASE FILE: Vanacore, R. et al. (2009) A Sulfilimine Bond Identified in Collagen IV. Science 325, 1230–1234.

The poster on the street

The wanted poster for Collagen IV sulfilimine

This is the photocopied wanted poster for Collagen IV sulfilimine, No. 117 of the exotic forty. They were made for noticeboards around Boston, Cambridge and the rest of the east coast.

Found one? Scan its QR code with your phone. If you're a signed-in player, the sighting goes on your record with +1 XP.

Not a player yet? Join the Epic Quest: the real role-playing game of Molecular Reality, a nanopore lab, with the CEO as gamemaster.